Detalhe da pesquisa
1.
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Nature
; 615(7950): 134-142, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36470304
2.
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
J Antimicrob Chemother
; 79(1): 172-178, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37995258
3.
Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study.
AIDS Res Ther
; 20(1): 20, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37004096
4.
A Holistic Review of the Preclinical Landscape for Long-Acting Anti-infective Drugs Using HIV as a Paradigm.
Clin Infect Dis
; 75(Suppl 4): S490-S497, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410386
5.
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Br J Clin Pharmacol
; 87(4): 2078-2088, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085781
6.
Genetic influence of ABCG2, UGT1A1 and NR1I2 on dolutegravir plasma pharmacokinetics.
J Antimicrob Chemother
; 75(5): 1259-1266, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32011683
7.
Pharmacokinetics of Efavirenz 400 mg Once Daily Coadministered With Isoniazid and Rifampicin in Human Immunodeficiency Virus-Infected Individuals.
Clin Infect Dis
; 68(3): 446-452, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30084943
8.
Meta-analysis of the effect of CYP2B6, CYP2A6, UGT2B7 and CAR polymorphisms on efavirenz plasma concentrations.
J Antimicrob Chemother
; 74(11): 3281-3290, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31369088
9.
Rifampicin effect on intracellular and plasma pharmacokinetics of tenofovir alafenamide.
J Antimicrob Chemother
; 74(6): 1670-1678, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30815689
10.
Effect of patient genetics on etonogestrel pharmacokinetics when combined with efavirenz or nevirapine ART.
J Antimicrob Chemother
; 74(10): 3003-3010, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31299074
11.
Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics of Efavirenz 400 mg Once Daily During Pregnancy and Post-Partum.
Clin Infect Dis
; 67(5): 785-790, 2018 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30124823
12.
Pregnancy affects nevirapine pharmacokinetics: evidence from a CYP2B6 genotype-guided observational study.
Pharmacogenet Genomics
; 26(8): 381-9, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27195527
13.
Hyaluronidase impacts exposures of long-acting injectable paliperidone palmitate in rodent models.
bioRxiv
; 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38496644
14.
Polymer-prodrug conjugates as candidates for degradable, long-acting implants, releasing the water-soluble nucleoside reverse-transcriptase inhibitor emtricitabine.
J Mater Chem B
; 11(48): 11532-11543, 2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37955203
15.
Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters.
Viruses
; 15(11)2023 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38005839
16.
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case.
bioRxiv
; 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35118468
17.
Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1228: 123823, 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37517355
18.
Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters.
Viruses
; 15(8)2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37632086
19.
Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.
Pharmaceutics
; 15(7)2023 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37514020
20.
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.
Nat Commun
; 14(1): 3583, 2023 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328472